METTL3-mediated N6-methyladenosine modification stimulates mitochondrial damage and ferroptosis of kidney tubular epithelial cells following acute kidney injury by modulating the stabilization of MDM2-p53-LMNB1 axis
Chenghuan Hu, Buyao Zhang, Shuangping Zhao
Topics & Concepts
ChemistryKidneyMitochondrionApoptosisAcute kidney injuryCell biologyMdm2Cancer researchProgrammed cell deathBiochemistryInternal medicineEndocrinologyBiologyMedicineRNA modifications and cancerCancer-related molecular mechanisms researchFerroptosis and cancer prognosis