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Co–N/C-900 metal–organic framework-derived nanozyme as a H<sub>2</sub>O<sub>2</sub>-free oxidase mimic for the colorimetric sensing of <scp>l</scp>-cysteine

Jian Chen, Song Hu, Yongliang Cai, Xia Liu, Yueqi Wu, Yihu Dai, Zhijuan Wang

2022The Analyst23 citationsDOI

Abstract

. However, the oxidation was inhibited after the addition of L-cysteine, and the blue color faded to colorless. Thus, Co-N/C-900 exhibited quite good oxidase-like activity with high catalytic efficiency. Therefore, a facile and efficient colorimetric method to sensitively determine L-cysteine with a low detection limit of 33 nM (S/N = 3) has been developed. Furthermore, favorable selectivity and anti-interference ability towards the determination of L-cysteine based on this approach have also been achieved. It is believed that this colorimetric method for the detection of L-cysteine based on Co-N/C-900 will show potential applications in bioscience and bioengineering.

Topics & Concepts

ChemistryCysteineDetection limitZeolitic imidazolate frameworkOxidase testImidazolateMetalMetal-organic frameworkSelectivityCatalysisCombinatorial chemistryInorganic chemistryEnzymeOrganic chemistryChromatographyAdsorptionAdvanced Nanomaterials in CatalysisAdvanced biosensing and bioanalysis techniquesNanocluster Synthesis and Applications
Co–N/C-900 metal–organic framework-derived nanozyme as a H<sub>2</sub>O<sub>2</sub>-free oxidase mimic for the colorimetric sensing of <scp>l</scp>-cysteine | Litcius