Apigenin and apigenin-7, 4′-O-dioctanoate protect against acrolein-aggravated inflammation via inhibiting the activation of NLRP3 inflammasome and HMGB1/MYD88/NF-κB signaling pathway in Human umbilical vein endothelial cells (HUVEC)
Jiangqiong Yu, Qingqing Jiang, Ning Liu, Daming Fan, Mingfu Wang, Yueliang Zhao
Topics & Concepts
InflammationInflammasomeChemistryAcroleinHMGB1Tumor necrosis factor alphaApigeninPharmacologyCancer researchBiochemistryReceptorImmunologyMedicineAntioxidantFlavonoidCatalysisAdvanced Glycation End Products researchHeme Oxygenase-1 and Carbon MonoxideInflammasome and immune disorders