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Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer

Yan Deng, Jia-chun Hu, Shuhua He, Bin Lou, Tingbo Ding, Jintong Yang, Mingguang Mo, De-yong Ye, Lu Zhou, Xian‐Cheng Jiang, Ker Yu, Jibin Dong

2020Acta Pharmacologica Sinica49 citationsDOIOpen Access PDF

Topics & Concepts

Cancer researchTriple-negative breast cancerTumor microenvironmentMacrophage polarizationTumor progressionImmune systemKnockout mouseBreast cancerCancerCD8ChemistryBiologyMacrophageMedicineImmunologyInternal medicineIn vitroReceptorBiochemistryImmune cells in cancerCancer Cells and MetastasisEpigenetics and DNA Methylation
Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer | Litcius