Palladium(II)‐Catalyzed Enantioselective C−H Alkenylation of Ferrocenecarboxylic Acid
Yanzhen Huang, Chao Pi, Xiuling Cui, Yangjie Wu
Abstract
Abstract The palladium‐catalyzed enantioselective C−H alkenylation of ferrocenecarboxylic acid has been developed. A series of 2‐alkenyl ferrocenecarboxylic acids with planar chirality were obtained using molecular oxygen as an oxidant. This protocol starts from less expensive and readily available starting materials and provides the target products as a key intermediate in organic synthesis. magnified image
Topics & Concepts
Enantioselective synthesisPalladiumChemistryChirality (physics)CatalysisMolecular oxygenPlanar chiralityCombinatorial chemistryOptically activeOrganic chemistryNambu–Jona-Lasinio modelChiral symmetry breakingQuantum mechanicsQuarkPhysicsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesCatalytic Cross-Coupling Reactions