A network pharmacology-based study on the mechanism of astragaloside IV alleviating renal fibrosis through the AKT1/GSK-3β pathway
Xinwei Yu, Qiming Xiao, Xixi Yu, Yu Cheng, Hao Lin, Zheng Xiang
Topics & Concepts
PharmacologyProtein kinase BAKT1PI3K/AKT/mTOR pathwayFibrosisSignal transductionPhosphorylationMechanism of actionMedicineKidneyGSK3BChemistryEndocrinologyInternal medicineBiochemistryIn vitroChronic Kidney Disease and DiabetesChemotherapy-induced organ toxicity mitigationTraditional Chinese Medicine Analysis