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Clinical and Analytical Evaluation of the Alinity m HR HPV Assay within the VALGENT-3 Framework

Sharonjit K. Dhillon, Anja Oštrbenk Valenčak, Lan Xu, Mario Poljak, Marc Arbyn

2021Journal of Clinical Microbiology18 citationsDOIOpen Access PDF

Abstract

e was used as a comparator. HPV genotype-specific concordance between Alinity m and the three comparator tests showed excellent agreement, with kappa values ranging from 0.82 to 1.00. In conclusion, Alinity m fulfills the international accuracy requirements for use in cervical cancer screening and shows excellent HPV genotype-specific concordance with three clinically validated HPV tests.

Topics & Concepts

Human papillomavirusCervical cancerPapillomaviridaeOncologyMedicineCervical cancer screeningVirologyInternal medicinePathologyCancerCervical Cancer and HPV ResearchMolecular Biology Techniques and ApplicationsAI in cancer detection