O<sub>2</sub>-Mediated Cu-Catalyzed Dehydrogenative Phenothiazination
Fang Xiao, Xingben Wang, Ben Ebel, Iris M. Oppel, Frédéric W. Patureau
Abstract
In contrast to what one can be led to believe upon inspecting some of the recent literature, the dehydrogenative phenothiazination reaction does not require onerous technologies, complicated setups, or advanced catalysts in order to be mild and sustainable. We demonstrate this herein with a most facile, cost-effective, and sustainable Cu(II) catalyzed method, under 1 atm of O 2 at room temperature in methanol, providing broad scope and high yields. These new results further set the dehydrogenative phenothiazination reaction among the green and practical coupling concepts of chemistry.
Topics & Concepts
CatalysisChemistryEnvironmental chemistryEnvironmental scienceOrganic chemistryPhenothiazines and Benzothiazines Synthesis and ActivitiesCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques