PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis
Elaine G. Garcia, Alexandra Veloso, Mariana L. Oliveira, James Allen, Siebe Loontiens, Dalton C. Brunson, Daniel Do, Chuan Yan, Robert Morris, Sowmya Iyer, Sara P. Garcia, N. Iftimia, Wouder Van Loocke, Filip Matthijssens, Karin M. McCarthy, João T. Barata, Frank Speleman, Tom Taghon, Alejandro Gutiérrez, Pieter Van Vlierberghe, Wilhelm Haas, Jessica S. Blackburn, David M. Langenau
Topics & Concepts
ZebrafishCancer researchBiologySignal transductionProtein tyrosine phosphataseApoptosisLeukemiaCell growthPhosphorylationNotch signaling pathwayT cellCell biologyImmunologyGeneticsGeneImmune systemProtein Tyrosine PhosphatasesAcute Lymphoblastic Leukemia researchRNA modifications and cancer