PTBP1-mediated biogenesis of circATIC promotes progression and cisplatin resistance of bladder cancer
Chenchen Huang, Yang Yang, Xiaofei Wang, Shuangchen Chen, Zhifu Liu, Zheng Li, Xingxing Tang, Qian Zhang
Abstract
Our study demonstrated that circATIC promoted BLca progression and DDP resistance, and could serve as a potential target for BLca treatment.
Topics & Concepts
CisplatinBladder cancerCancer researchUrothelial cancerResistance (ecology)BiogenesisBiologyCancerMedicineOncologyInternal medicineGeneticsGeneChemotherapyEcologyCircular RNAs in diseasesMicroRNA in disease regulationGenomics, phytochemicals, and oxidative stress