Inhibition of STX17–SNAP29–VAMP8 complex formation by costunolide sensitizes ovarian cancer cells to cisplatin via the AMPK/mTOR signaling pathway
Xiao Liang, Chunlei Yu, Yunhong Tian, Xiaocong Xiang, Yuexi Luo
Topics & Concepts
AutophagyAMPKPI3K/AKT/mTOR pathwaymTORC1CisplatinCancer researchCell biologyChemistryLysosomeBiologySignal transductionInternal medicinePhosphorylationApoptosisChemotherapyMedicineBiochemistryProtein kinase AEnzymeAutophagy in Disease and TherapySirtuins and Resveratrol in MedicineHistone Deacetylase Inhibitors Research