Tertiary Prevention of HCC in Chronic Hepatitis B or C Infected Patients
Wei Teng, Yen‐Chun Liu, Wen‐Juei Jeng, Chien‐Wei Su
Abstract
Hepatocellular carcinoma (HCC) ranks as a leading cause of common cancer and cancer-related death. The major etiology of HCC is due to chronic hepatitis virus including HBV and HCV infections. Scheduled HCC surveillance in high risk populations improves the early detection rate and the feasibility of curative treatment. However, high HCC recurrence rate still accounts for the poor prognosis of HCC patients. In this article, we critically review the pathogenesis of viral hepatitis-related hepatocellular carcinoma and the evidence of tertiary prevention efficacy by current available antiviral treatment, and discuss the knowledge gap in viral hepatitis-related HCC tertiary prevention.
Topics & Concepts
Hepatocellular carcinomaMedicineLiver cancerEtiologyInternal medicineViral hepatitisHepatitis C virusChronic hepatitisHepatitis B virusHepatitis BCancerHepatitis CAntiviral treatmentGastroenterologyVirusOncologyVirologyHepatitis B Virus StudiesHepatocellular Carcinoma Treatment and PrognosisLiver Disease Diagnosis and Treatment