Glyphosate-triggered hepatocyte ferroptosis via suppressing Nrf2/GSH/GPX4 axis exacerbates hepatotoxicity
Jingbo Liu, Guangcheng Yang, Hongna Zhang
Topics & Concepts
GPX4GlutathioneHepatocyteToxicityReactive oxygen speciesIn vivoChemistryProgrammed cell deathCell biologyIn vitroPharmacologyBiochemistryBiologyApoptosisGeneticsEnzymeGlutathione peroxidaseOrganic chemistryEpigenetics and DNA MethylationFolate and B Vitamins ResearchArsenic contamination and mitigation