Aerosolizable siRNA-encapsulated solid lipid nanoparticles prepared by thin-film freeze-drying for potential pulmonary delivery
Jieliang Wang, Mahmoud S. Hanafy, Haiyue Xu, J. Sánchez Leal, Yufeng Zhai, Debadyuti Ghosh, Robert O. Williams, Hugh D. C. Smyth, Zhengrong Cui
Topics & Concepts
DispersitySolid lipid nanoparticleSpray dryingZeta potentialNanoparticlePolyethylene glycolFreeze-dryingParticle sizeMaterials scienceLecithinDrug deliveryChemical engineeringSolventPEG ratioDrug carrierChemistryChromatographyNanotechnologyOrganic chemistryPolymer chemistryEconomicsEngineeringFinanceInhalation and Respiratory Drug DeliveryAdvancements in Transdermal Drug DeliveryMicroencapsulation and Drying Processes