Increased CYR61 expression activates CCND1/c-Myc pathway to promote nasal epithelial cells proliferation in chronic rhinosinusitis with nasal polyps
Chunyu Luo, Ying Zhu, Jiayao Zhou, Xiwen Sun, Shiyao Zhang, Shaolin Tan, Zhipeng Li, Hai Lin, Weitian Zhang
Topics & Concepts
Nasal polypsCyclin D1CYR61Cancer researchBiologyPathologyEpitheliumDownregulation and upregulationCell cycleCellMedicineImmunologyInternal medicineReceptorCTGFGrowth factorGeneBiochemistryGeneticsConnective Tissue Growth Factor ResearchSinusitis and nasal conditionsIL-33, ST2, and ILC Pathways