Aerobic oxyfunctionalization of alkynes by a bioinspired flavin–metal ion photocatalytic system
Duyi Shen, Fubi Zhong, Ling‐Hui Li, Haixing Zhang, Ting Ren, Chaoyue Sun, Bin Wang, Mian Guo, Mianran Chao, Shunichi Fukuzumi
Abstract
α-Keto ketals and benzannulated oxo-spiroketals have been regioselectively synthesized using a Sc 3+ -coordinated riboflavin tetraacetate photocatalyst with electron-deficient alkynes and alkynediols, respectively.
Topics & Concepts
ChemistryFlavin groupRiboflavinPhotocatalysisMetalPhotochemistryMetal ions in aqueous solutionCombinatorial chemistryIonOrganic chemistryCatalysisBiochemistryEnzymePolyoxometalates: Synthesis and ApplicationsOxidative Organic Chemistry ReactionsRadical Photochemical Reactions