Caffeoyl substitution decreased the binding and inhibitory activity of quinic acid against α-amylase: The reason why chlorogenic acid is a relatively weak enzyme inhibitor
Yi Song, Wenyue Li, Hefei Yang, Xiaoke Peng, Xi Yang, Xuebo Liu, Lijun Sun
Topics & Concepts
Isothermal titration calorimetryChemistryChlorogenic acidCaffeic acidAmylaseQuinic acidEnzymeBiochemistryDissociation constantStereochemistryFluorescenceKineticsIC50Quenching (fluorescence)ChromatographyIn vitroAntioxidantReceptorQuantum mechanicsPhysicsEnzyme Production and CharacterizationProtein Interaction Studies and Fluorescence AnalysisNatural Antidiabetic Agents Studies