Documentation of bioactive principles of the flower from Caralluma retrospiciens (Ehrenb) and in vitro antibacterial activity – Part B
Saad S. Alqahtani, Hafiz A. Makeen, Santhosh Joseph Menachery, Sivakumar S. Moni
Abstract
The purpose of this study was to explore the biocomponents of flowers from Caralluma retrospiciens (Ehrenb). The study investigated the FT-IR and GC–MS spectral analysis of flower from C. retrospiciens (Ehrenb). A flower concentrate (FC) was prepared and the functional groups were determined by FT-IR spectroscopy study. FT-IR analysis showed the presence of significant compounds at frequency 3287.45, 2850.32, 2595.91, 2524.69, 2041.07 cm−1. The GC–MS study demonstrated the presence of unique pharmaceutically important compounds. The extract was characterized by the presence of unique compounds such as “7,8-Epoxylanostan-11-ol, 3-acetoxy”, “Pregnan-20-one, 5,6-epoxy-3-hydroxy-, (3á,5á,6á)-”, “Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, methyl ester”, “Hexadecanoic acid, methyl ester”, “Dasycarpidan-1-methanol, acetate”, etc. The antibacterial effect of the FC showed a wide spectrum of activity against the screened human pathogenic bacteria. The activity was predominantly against Gram-negative bacteria.