First Known Human Death After Infection With the Avian Influenza A/H3N8 Virus: Guangdong Province, China, March 2023
Yali Zhuang, Man Wang, Lijun Liang, Yunxia Mao, Kaibin Wang, Shuhuan Yang, Aiping Deng, Kewen Zeng, Yingtao Zhang, Guanting Zhang, Min Kang, Baisheng Li, Meng Zhang, S. Ye
Abstract
Here, we report on a case of human infection with the H3N8 avian influenza virus. The patient had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without mammalian-adaptive mutations. This suggests that avian influenza (A/H3N8) virus infection could be lethal for immunocompromised persons.
Topics & Concepts
VirusVirologyInfluenza A virus subtype H5N1MedicineGeneInfluenza A virusSouthern chinaBiologyChinaGeneticsLawPolitical scienceInfluenza Virus Research StudiesViral Infections and VectorsAnimal Disease Management and Epidemiology