Pathogenic Aβ generation in familial Alzheimer’s disease: novel mechanistic insights and therapeutic implications
Johannes Trambauer, Akio Fukumori, Harald Steiner
Topics & Concepts
PresenilinAmyloid precursor proteinAmyloid precursor protein secretaseNeuroscienceDiseaseMechanism (biology)Alzheimer's diseaseBiologyChemistryMedicineInternal medicinePhilosophyEpistemologyAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery Methods