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Drivers and barriers of AI adoption and use in scientific research

Stefano Bianchini, Moritz Müller, Pierre Pelletier

2025Technological Forecasting and Social Change9 citationsDOIOpen Access PDF

Abstract

We study the early adoption and use of artificial intelligence (AI) in scientific research. Using a large dataset of publications from OpenAlex (all fields, up to 2024) and building on theories of scientific and technical human capital, we identify key factors that influence AI adoption. We find that early adopters were domain scientists embedded in AI-rich collaboration networks and affiliated with institutions with strong AI credentials. Access to high-performance computing (HPC) mattered only in a few scientific disciplines, such as biology and medical sciences. More recently, as tools like Large Language Models (LLMs) have diffused, AI has become more accessible, and institutional advantages appear to matter less. However, social capital—especially ties to AI-experienced collaborators and early-career researchers—remains a persistent driver of adoption. We discuss the implications for science policy and the organization of research in the age of AI. • Factors driving and hindering AI adoption in science. • AI adoption shaped by social, institutional, and individual factors. • Collaboration networks and team composition strongly predict adoption. • Access to computing resources is generally not a major barrier. • Institutional and technical factors matter less after LLMs emerge.

Topics & Concepts

BusinessRegional scienceData scienceKnowledge managementManagement scienceComputer scienceSociologyEconomicsArtificial Intelligence in Healthcare and EducationBig Data and Business IntelligenceEthics and Social Impacts of AI
Drivers and barriers of AI adoption and use in scientific research | Litcius