Impact of Temporary Storage Conditions on the Viability of Streptococcus pneumoniae in Saliva
Orchid M. Allicock, Anna York, Pari Waghela, Devyn Yolda-Carr, Daniel M. Weinberger, Anne L. Wyllie
Abstract
For pneumococcal carriage studies, saliva is a sample type that can overcome some of the issues typically seen with nasopharyngeal and oropharyngeal swabs. Understanding the limitations of saliva as a sample type is important for maximizing its use. This study sought to better understand how different storage conditions and freeze-thaw cycles affect pneumococcal survival over time. These findings support the use of saliva as an alternative sample type for pneumococcal carriage studies, particularly in remote or low-resource settings with reduced access to health care facilities.
Topics & Concepts
Streptococcus pneumoniaeSalivaMicrobiologyMedicineBiologyInternal medicineAntibioticsPneumonia and Respiratory InfectionsRespiratory viral infections researchBacterial Infections and Vaccines