Litcius/Paper detail

Discovery of novel thienopyridine indole derivatives as inhibitors of tubulin polymerization targeting the colchicine-binding site with potent anticancer activities

Wen‐Bo Liu, Weiguang Yang, Ji Wu, Bingbing Chen, Yifei Du, Jin-Bo Niu, Jian Song, Sai‐Yang Zhang

2025European Journal of Medicinal Chemistry17 citationsDOI

Topics & Concepts

ChemistryColchicineThienopyridineTubulinIndole testPharmacologyMicrotubuleStereochemistryCombinatorial chemistryBiochemistryInternal medicineCell biologyAspirinClopidogrelBiologyMedicineSynthesis and biological activitySynthesis and Biological EvaluationMulticomponent Synthesis of Heterocycles