Hyper-Crosslinked Porous Chiral Phosphoric Acids: Robust Solid Organocatalysts for Asymmetric Dearomatization Reactions

Abstract

Knitting rigid aromatic building blocks using external crosslinkers has been developed into an effective strategy for the synthesis of porous polymers in recent years. Here, we report the synthesis of porous chiral phosphoric acids by this strategy. Moreover, these porous chiral phosphoric acids were found to enable highly enantioselective dearomatization reactions. Remarkably, after being reused for 10 runs, no obvious loss in catalytic activity and selectivity was observed. The features of high reactivity, selectivity, stability, and recyclability of these hyper-crosslinked porous chiral phosphoric acids are significant for practical catalyst design.

Topics & Concepts