NHC-gold(I)-alkyne complexes induced hepatocellular carcinoma cell death through bioorthogonal activation by palladium complex in living system
Yunlong Lu, Yuan‐Hao Liu, Zhenlin Liang, Xiaoyan Ma, Lijuan Liu, Zhenfan Wen, Iogann Tolbatov, Alessandro Marrone, Wukun Liu, Alessandro Marrone, Wukun Liu
Topics & Concepts
Bioorthogonal chemistryThioredoxin reductaseChemistryAlkyneCarbeneHepatocellular carcinomaCombinatorial chemistryCatalysisPalladiumBiochemistryThioredoxinCancer researchEnzymeBiologyClick chemistryClick Chemistry and ApplicationsPeptidase Inhibition and AnalysisChemical Synthesis and Analysis