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Copper induces liver lipotoxicity disease by up-regulating Nrf2 expression via the activation of MTF-1 and inhibition of SP1/Fyn pathway

Chong-Chao Zhong, Tao Zhao, Christer Högstrand, Chang-Chun Song, Ester Zito, Xiao-Ying Tan, Yi-Chuang Xu, Yu–Feng Song, Xiaolei Wei, Zhi Luo

2023Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease23 citationsDOI

Topics & Concepts

LipotoxicityFYNTranscription factorCell biologyInternal medicineEndocrinologyChemistryBiologyPromoterCancer researchSignal transductionGene expressionMedicineGeneBiochemistryObesityProto-oncogene tyrosine-protein kinase SrcInsulin resistanceGenomics, phytochemicals, and oxidative stressLiver Disease Diagnosis and TreatmentGlutathione Transferases and Polymorphisms
Copper induces liver lipotoxicity disease by up-regulating Nrf2 expression via the activation of MTF-1 and inhibition of SP1/Fyn pathway | Litcius