CCAT2 knockdown inhibits cell growth, and migration and promotes apoptosis through regulating the hsa-mir-145-5p/AKT3/mTOR axis in tamoxifen-resistant MCF7 cells
Foruzan Moradi, Fatemeh Mohajerani, Majid Sadeghizadeh
Topics & Concepts
Gene knockdownPI3K/AKT/mTOR pathwayCancer researchBiologyEstrogen receptorLong non-coding RNAmicroRNABreast cancerTamoxifenApoptosisCell growthGeneCancerRNAGeneticsCancer-related molecular mechanisms researchMicroRNA in disease regulationFerroptosis and cancer prognosis