Repurposing elesclomol, an investigational drug for the treatment of copper metabolism disorders
Vishal M. Gohil
Abstract
Copper serves as a structural and catalytic cofactor for a variety of enzymes in aerobic organisms. Though present in trace amounts, copper is essential for numerous biochemical processes including...
Topics & Concepts
Drug repositioningRepurposingDrug discoveryDrugCopperDrug metabolismDrug developmentAutophagyDrug targetChemistryComputational biologyBiochemistryPharmacologyBiologyApoptosisOrganic chemistryEcologyTrace Elements in HealthHeavy Metal Exposure and ToxicityAluminum toxicity and tolerance in plants and animals