Copper-catalyzed intermolecular carboesterification of unactivated aliphatic alkenes with α-carbonyl alkyl bromides <i>via</i> a SET process: efficient synthesis of γ-lactones
Cancan Feng, Youcai Zhu, Zhen Liu, Fan Yang, Yangjie Wu
Abstract
A novel and efficient copper-catalyzed carboesterification of unactivated alkenes with α-carbonyl alkyl bromides for the synthesis of γ-lactones derivatives has been developed.
Topics & Concepts
ChemistryAlkylCatalysisIntermolecular forceCopperOrganic chemistryCombinatorial chemistryMedicinal chemistryMoleculeCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsCarbon dioxide utilization in catalysis