Cascaded <i>de novo</i> biosynthesis of lacto-proteins from CO<sub>2</sub> by engineered <i>Pichia pastoris</i>
Xueqin Lv, Shixiu Cui, Jie Chen, Lingrui Wang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xiaohao Liu, Jian Chen, Rodrigo Ledesma‐Amaro, Long Liu
Abstract
A chemo-biocascade catalysis (CBCC) system was constructed that combines spatially separated CO 2 thermo-catalysis with yeast fermentation to efficiently convert CO 2 to lacto-proteins.
Topics & Concepts
Pichia pastorisBiosynthesisPichiaChemistryBiochemistryComputational biologyCombinatorial chemistryStereochemistryBiologyGeneRecombinant DNAMicrobial Metabolic Engineering and BioproductionEnzyme Catalysis and ImmobilizationAgriculture Sustainability and Environmental Impact