Host-guest inclusion for enhancing anticancer activity of pemetrexed against lung carcinoma and decreasing cytotoxicity to normal cells
Junyi Chen, Yahan Zhang, Yadan Zhang, Liang Zhao, Longming Chen, Yao Chai, Zhao Meng, Xueshun Jia, Qingbin Meng, Chunju Li
Topics & Concepts
CytotoxicityPemetrexedChemistryATP hydrolysisDephosphorylationHydrolysisOsteosarcomaAlkaline phosphatasePharmacologyCombinatorial chemistryCancer researchBiochemistryIn vitroChemotherapyCisplatinPhosphatasePhosphorylationEnzymeMedicineInternal medicineATPaseSupramolecular Chemistry and ComplexesMetal-Organic Frameworks: Synthesis and ApplicationsRadiopharmaceutical Chemistry and Applications