Magnesium Ammonium Phosphate Composite Cell-Laden Hydrogel Promotes Osteogenesis and Angiogenesis <i>In Vitro</i>
Chang Liu, Guangzheng Yang, Mingliang Zhou, Xiangkai Zhang, Xiaolin Wu, Peishi Wu, Xiaoyu Gu, Xinquan Jiang
Abstract
during degradation. The cell delivery system using MgP improved the laden-cell viability, upregulated the expression of osteogenic and angiogenic-differentiation-related genes, and promoted cell migration. Overall, the modifications made to the GelMA in this study improved osteoinduction and demonstrated great potential for application in vascularized bone tissue regeneration.
Topics & Concepts
StruviteChemistrySelf-healing hydrogelsAngiogenesisUmbilical veinDental pulp stem cellsBiomedical engineeringGelatinPhosphateCell biologyIn vitroDentistryBiochemistryPolymer chemistryMedicineBiologyInternal medicineBone Tissue Engineering Materials3D Printing in Biomedical ResearchGraphene and Nanomaterials Applications