Signaling in <i>Acinetobacter baumannii</i> : Quorum sensing and nucleotide second messengers
Binbin Cui, Ganjin Peng, Liu-En Wang, Yinyue Deng
Abstract
Quorum sensing (QS) is a widely conserved cell-cell communication mechanism through which bacterial cells control physiological functions and pathogenesis. Additionally, intracellular nucleotide second messengers (NSMs) have been shown to regulate diverse bacterial functions. Acinetobacter baumannii is now a substantial threat and a considerable challenge worldwide, and recent research indicates that A. baumannii not only utilizes QS systems but also employs NSMs to regulate phenotypes and virulence.
Topics & Concepts
Quorum sensingAcinetobacter baumanniiSecond messenger systemNucleotideAcinetobacterBiologyComputational biologyMicrobiologyBiofilmSignal transductionBacteriaCell biologyGeneticsAntibioticsPseudomonas aeruginosaGeneAntibiotic Resistance in BacteriaVibrio bacteria research studiesBacterial biofilms and quorum sensing