Litcius/Paper detail

KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells

Krishnan K. Mahadevan, Kathleen M. McAndrews, Valerie S. LeBleu, Sujuan Yang, Hengyu Lyu, Bingrui Li, Amari M. Sockwell, Michelle L. Kirtley, Sami J. Morse, Barbara A. Moreno Diaz, Michael P. Kim, Ningping Feng, Anastasia M. Lopez, Paola A. Guerrero, Francesca Paradiso, Hikaru Sugimoto, Kent A. Arian, Haoqiang Ying, Yasaman Barekatain, Lakshmi Kavitha Sthanam, Patience J. Kelly, Anirban Maitra, Timothy P. Heffernan, Raghu Kalluri

2023Cancer Cell228 citationsDOIOpen Access PDF

Topics & Concepts

Cancer researchPancreatic cancerTumor microenvironmentCD8EffectorBiologyCytotoxic T cellCancer cellCancerImmune systemImmunologyIn vitroTumor cellsGeneticsBiochemistryPancreatic and Hepatic Oncology ResearchPhagocytosis and Immune RegulationCancer Immunotherapy and Biomarkers