Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor
Xiaoxing Huang, Youwang Wang, Cong Yu, Hui Zhang, Qiang Ru, Xinxin Li, Kai Song, Min Zhou, Ping Zhu
Topics & Concepts
alpha-2-MacroglobulinProteasesAlpha (finance)ProteaseTrypsinProtease inhibitor (pharmacology)Transformation (genetics)ChemistryMacroglobulinEnzymeBiologyBiochemistryImmunologyMedicineVirusViral loadConstruct validityNursingAntiretroviral therapyGenePatient satisfactionGlycosylation and Glycoproteins ResearchBlood properties and coagulationProtein purification and stability