Next-generation forward genetic screens: uniting high-throughput perturbations with single-cell analysis
John Morris, Jennifer S. Sun, Neville E. Sanjana
Topics & Concepts
CRISPRBiologyGenome editingComputational biologyEpigenomePhenotypeGenomeTranscriptomeGenome engineeringCRISPR interferenceGeneGeneticsMassively parallelComputer scienceGene expressionDNA methylationParallel computingCRISPR and Genetic EngineeringSingle-cell and spatial transcriptomicsGene Regulatory Network Analysis