Rabbit IgG-imprinted nanoMIPs by solid phase synthesis: the effect of cross-linkers on their affinity and selectivity
Matteo Chiarello, Laura Anfossi, Simone Cavalera, Fabio Di Nardo, Thea Serra, Fabrizio Sordello, Claudio Baggiani
Abstract
L), medium to high imprinting factors (BIS: 12.3, EDAM: 5.5, NOBE: 7.2, and GDMA: 11.6) and good selectivity towards other proteins but markedly dependent on the structure of the cross-linker, confirming the importance of the latter in the SPS of imprinted nanopolymers.
Topics & Concepts
SelectivityLinkerPhase (matter)Solid-phase synthesisMaterials scienceCombinatorial chemistryMolecularly imprinted polymerChemistryOrganic chemistryBiochemistryCatalysisPeptideComputer scienceOperating systemAnalytical chemistry methods developmentPolymer Surface Interaction StudiesMicrofluidic and Capillary Electrophoresis Applications