Na<sub>2</sub>Ca(HPO<sub>4</sub>)<sub>2,</sub>an Efficient, Reusable Eco-Friendly Catalyst for the Synthesis of 1,8-Dioxo-Octahydroxanthenes and Biscoumarin Derivatives
Soukaina Chehab, Youssef Merroun, Rachida Ghaılane, Saı̈d Boukhris, Abdelaziz Souızı
Abstract
In this paper, Na2Ca(HPO4)2 was used for the first time as a heterogeneous catalyst for efficient and green synthesis of 1,8-dioxo-octahydroxanthenes and biscoumarin derivatives. Under optimal conditions, the products were obtained with excellent yields in a short reaction time. This developed procedure has shown several advantages: avoiding toxic solvents, catalyst, simple handling, mild conditions, easy recovery, and catalyst reuse.Na2Ca(HPO4)2 as a heterogeneous catalyst guarantees an environmentally friendly process; it can be considered an alternative to the other previously reported synthesis methods.
Topics & Concepts
ChemistryEnvironmentally friendlyCatalysisHeterogeneous catalysisReuseCombinatorial chemistryReaction conditionsOrganic chemistryChemical engineeringWaste managementEngineeringEcologyBiologyMulticomponent Synthesis of HeterocyclesSynthesis of Organic CompoundsSynthesis of Indole Derivatives