Breaking the final barrier: Evolution of cationic and ionizable lipid structure in lipid nanoparticles to escape the endosome
Kaitlin Mrksich, Marshall S. Padilla, Michael J. Mitchell
Topics & Concepts
EndosomeNucleic acidRational designCytosolCytoplasmCationic polymerizationChemistryDrug deliveryCell biologyBiophysicsBiochemistryNanotechnologyBiologyEnzymeCellMaterials scienceOrganic chemistryRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesLipid Membrane Structure and Behavior