UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
Chuan He, Xixin Xing, Hsin-Yi Chen, Minling Gao, Jie Shi, Bolin Xiang, Xiangling Xiao, Yishuang Sun, Haisheng Yu, Gaoshan Xu, Yingmeng Yao, Zuosong Xie, Yujie Xing, Bugi Ratno Budiarto, Shih‐Yu Chen, Yang Gao, Yu-Ru Lee, Jinfang Zhang
Topics & Concepts
BiologyCytotoxic T cellUbiquitin ligaseCancer researchCD8UbiquitinCell biologyCancer immunotherapyT cellConditional gene knockoutImmune systemImmunotherapyPhosphorylationImmunologyBiochemistryPhenotypeIn vitroGeneUbiquitin and proteasome pathwaysCAR-T cell therapy researchPeptidase Inhibition and Analysis