Multicenter Evaluation of the Xpert Carba-R Assay for Detection and Identification of Carbapenemase Genes in Sputum Specimens
Zhen Cai, Jia Tao, Tianye Jia, Hongyu Fu, Xin Zhang, Mei Zhao, Hong Du, Hua Yu, Bin Shan, Bin Huang, Liang Chen, Yi‐Wei Tang, Wei Jia, Fen Qu
Abstract
Rapid diagnosis of infections caused by carbapenem-resistant Enterobacteriaceae (CRE) is crucial for proper treatment and infection control. The Xpert Carba-R assay is a qualitative multiplex real-time PCR method that qualitatively detects and differentiates five common carbapenemase genes ( bla KPC , bla NDM , bla VIM , bla OXA-48 , and bla IMP ) directly from rectal swabs or purified colonies within approximately 1 h.
Topics & Concepts
Klebsiella pneumoniaeBiologySputumMicrobiologyEnterobacter aerogenesEnterobacter cloacaeCitrobacter freundiiKlebsiella oxytocaEnterobacteriaceaeCarbapenemSerratia marcescensGeneEscherichia coliMedicineAntibioticsTuberculosisGeneticsPathologyAntibiotic Resistance in BacteriaBacterial Identification and Susceptibility TestingMycobacterium research and diagnosis