Epidemiology and Antimicrobial Resistance Profiles of the <i>Nocardia</i> Species in China, 2009 to 2021
Hao Wang, Yue Zhu, Qiaozhen Cui, Wenming Wu, Gang Li, Dongke Chen, Lili Xiang, Jiuxin Qu, Dongyan Shi, Binghuai Lu
Abstract
The genus Nocardia has the potential to cause nocardiosis, which might be underrecognized and underdiagnosed. Herein, the demographical features of 441 nonrepetitive nocardiosis cases and species distribution of their Nocardia strains in China, 2009 to 2021, are summarized. The susceptibility profiles for 15 antibiotics against all of the above Nocardia strains were also determined by the broth microdilution method. To date, this is the largest study on the genus Nocardia contributing to nocardiosis in China. Our study will be helpful for understanding the species diversity of Nocardia isolates distributed in China and for decision-making in the context of nocardiosis diagnosis and treatment.