New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry
Deling Shi, Huimin Zhao, Changkai Bu, Keith Fraser, Haoran Wang, Jonathan S. Dordick, Robert J. Linhardt, Fuming Zhang, Feng Shi, Lianli Chi
Topics & Concepts
HeparinChemistryTetramerLow molecular weight heparinPlatelet factor 4Mass spectrometryChromatographyBiochemistryEnzymeHeparin-Induced Thrombocytopenia and ThrombosisProteoglycans and glycosaminoglycans researchPlatelet Disorders and Treatments