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Development of biotin decorated Olaparib loaded cationic lipopolymeric hybrid nanoparticle and evaluation of its anticancer effect and pharmacokinetics for triple negative breast cancer

Rajesh Pradhan, Shobha Kumari, Himaja Ambati, Tarun Patel, Balaram Ghosh, Anu Puri, Sunil Kumar Dubey, Rajeev Taliyan

2024Journal of Drug Delivery Science and Technology17 citationsDOI

Topics & Concepts

OlaparibPharmacokineticsPARP inhibitorChemistryBioavailabilityPharmacologyMaterials scienceMedicineBiochemistryPoly ADP ribose polymerasePolymeraseGenePARP inhibition in cancer therapyCell death mechanisms and regulationNeutropenia and Cancer Infections
Development of biotin decorated Olaparib loaded cationic lipopolymeric hybrid nanoparticle and evaluation of its anticancer effect and pharmacokinetics for triple negative breast cancer | Litcius