Effects of the <i>CYP2C19</i> LoF Allele on Major Adverse Cardiovascular Events Associated with Clopidogrel in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis
Mohitosh Biswas, Chonlaphat Sukasem, Most. Sumaiya Khatun Kali, Baharudin Ibrahim
Abstract
LoF alleles, who underwent PCI and were treated with clopidogrel were correlated with significantly increased risk of MACE compared with noncarriers.
Topics & Concepts
ClopidogrelMedicineAcute coronary syndromePercutaneous coronary interventionCYP2C19Internal medicineCardiologyMeta-analysisAdverse effectAspirinMyocardial infarctionMetabolismCytochrome P450Antiplatelet Therapy and Cardiovascular DiseasesDiabetes Treatment and ManagementLipoproteins and Cardiovascular Health