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Disrupting the DNA Binding of EGR-1 with a Small-Molecule Inhibitor Ameliorates 2,4-Dinitrochlorobenzene-Induced Skin Inflammation

Hyunjin Yeo, Sung Shin Ahn, Jeong‐Yeon Lee, Euitaek Jung, Munki Jeong, Gi-Sue Kang, Seunghyun Ahn, Youngshim Lee, Dongsoo Koh, Young Han Lee, Yoongho Lim, Soon Young Shin

2021Journal of Investigative Dermatology20 citationsDOIOpen Access PDF

Topics & Concepts

InflammationTumor necrosis factor alphaMolecular biologyTranscription factorApoptosisDownregulation and upregulationChemistryHaCaTBiologyCancer researchCell biologyGeneImmunologyGeneticsCell cultureIL-33, ST2, and ILC PathwaysImmune Response and InflammationImmune Cell Function and Interaction
Disrupting the DNA Binding of EGR-1 with a Small-Molecule Inhibitor Ameliorates 2,4-Dinitrochlorobenzene-Induced Skin Inflammation | Litcius