Hypoxia-derived mesenchymal stem-cell exosomes delivering naringin enhance osteoblast migration and fracture healing by upregulating integrin β1 via the BDNF-TrkB/ERK1/2 signaling pathway
Rui Yao, Yonglun Luo, Hongzhen Tian
Abstract
European Cells & Materials Journal - Open and Free Access - The Official Research Journal of AOCMF, AOTrauma, European Orthopaedic Research Society (EORS), Swiss Society for Biomaterials (SSB) and Tissue & Cell Engineering Society (TCES)
Topics & Concepts
Mesenchymal stem cellCell biologyMicrovesiclesHypoxia (environmental)OsteoblastNaringinTropomyosin receptor kinase BChemistryBiologyNeurotrophic factorsmicroRNAReceptorBiochemistryOxygenChromatographyIn vitroOrganic chemistryGeneBone Metabolism and Diseasesinterferon and immune responsesOsteoarthritis Treatment and Mechanisms