Litcius/Paper detail

Exploring new targets and chemical space with affinity selection-mass spectrometry

Renaud Prudent, D. Allen Annis, Peter J. Dandliker, Jean‐Yves Ortholand, Didier Roche

2020Nature Reviews Chemistry104 citationsDOI

Topics & Concepts

Chemical spaceDrug discoveryComputational biologyHigh-throughput screeningMass spectrometryScreening techniquesSmall moleculeChemistrySelection (genetic algorithm)Computer scienceDrug targetCombinatorial chemistryNanotechnologyBiochemical engineeringBioinformaticsBiologyMachine learningMaterials scienceChromatographyBiochemistryEngineeringComputational Drug Discovery MethodsChemical Synthesis and AnalysisProtein Degradation and Inhibitors