CRP-Like Transcriptional Regulator MrpC Curbs c-di-GMP and 3′,3′-cGAMP Nucleotide Levels during Development in Myxococcus xanthus
Sofya Kuzmich, Patrick Blumenkamp, Doreen Meier, Dobromir Szadkowski, Alexander Goesmann, Anke Becker, Lotte Søgaard‐Andersen
Abstract
The second messenger c-di-GMP is important during both stages of the nutrient-regulated biphasic life cycle of Myxococcus xanthus with the formation of predatory swarms in the presence of nutrients and spore-filled fruiting bodies in the absence of nutrients. However, different enzymes involved in c-di-GMP synthesis and degradation are important during distinct life cycle stages.
Topics & Concepts
Myxococcus xanthusCell biologyNucleotideBiologyEnzymeRegulatorChemistryGeneBiochemistryMutantBacterial Genetics and BiotechnologyGenomics and Phylogenetic StudiesProtist diversity and phylogeny