Protective role of sirtuin3 against oxidative stress and NLRP3 inflammasome in cholesterol accumulation and foam cell formation of macrophages with ox-LDL-stimulation
Yue Ding, Weiwei Gong, Shuping Zhang, Jieru Shen, Xiao Liu, Yuqin Wang, Yun Chen, Guoliang Meng
Topics & Concepts
SIRT3Oxidative stressInflammasomeFoam cellInflammationCell biologyChemistryReactive oxygen speciesMitochondrial ROSMitochondrionCholesterolLipoproteinBiologyBiochemistryImmunologySirtuinAcetylationGeneMedicinal plant effects and applicationsFlavonoids in Medical ResearchBiological Activity of Diterpenoids and Biflavonoids